HC-Lab - Humidity Controller
The HC-Lab is designed for crystal dehydration experiments (ref. 1 to 3). It delivers a continuous flux of humid air with a controlled Relative Humidity (RH) in the immediate crystal environment.
- Large RH range: 30.0 % to 99.8 % (@ room temperature)
- High stability: ±0.05 % RMS
- Small dimensions adapted to home laboratory and synchrotron hutch with limited free space
- Sample visualization and sample size tracking via image recognition
- Parameter monitoring over time (sample temperature, RH value)
- Python scripting
- Remote Control
Moreover, the HC-Lab can be combined with the Rapid Nozzle Exchanger REX to automate the nozzle exchange between the HC-Lab humidity nozzle and the cryo nozzle while maintaining the alignment with respect to the sample/crystal.
Wheeler, M., Müller, U., et al. (2015). "Automation and Experience of Controlled Crystal Dehydration: Results from the European Synchrotron HC1 Collaboration". Cryst. Growth Des., 15 (3), pp 1043–1054
Wheeler, M. J., S. Russi, et al. (2012). "Measurement of the equilibrium relative humidity for common precipitant concentrations: facilitating controlled dehydration experiments." Acta Crystallogr Sect F Struct Biol Cryst Commun 68 (1): 111-114.
Russo Krauss, I., F. Sica, et al. (2012). "Increasing the X-ray Diffraction Power of Protein Crystals by Dehydration: The Case of Bovine Serum Albumin and a Survey of Literature Data." Int J Mol Sci 13 (3): 3782-3800.