REX - Rapid Nozzle Exchanger
REX is a remote controlled nozzle changer designed to be combined with HC-Lab for crystal dehydration experiments on crystallography beamlines.
It is also an automatic solution to optimize operating time on high throughput x-ray beamlines.
REX manipulates 2 nozzles and gives the possibility to automatically switch between them. For crystal dehydration experiments, REX can switch between the cryo nozzle and the humidity nozzle of HC-Lab.
Remote nozzle exchange
- Stable nozzle alignment
- Both nozzles are mounted and aligned on REX only once: they always remain aligned wth respect to the sample position no matter number of automatic nozzle movements which are performed
- No need of manual intervention
- No need of staff intervention inside the hutch: external beamline users can exchange the nozzles in an easy and fast way without needed a helping hand from beamline scientist.
- Fully retract (100 mm) the cryo-nozzle and mount a crystal at room temperature. Then, quickly move in the humidity-nozzle and perform your de/humidification experiment.
Maintains cryo-cooling during sample change
- When mounting a frozen sample with a robot (like a 6-axis changer robot) the cryo-nozzle can be retracted to procure sufficient free space to mount the crystal but with still a cold stream to protect the crystal.
Adapted to dehydration experiments with HC-Lab (or HC1)
- Support HC-Lab & HC1 humidity nozzle
- A large variety of cryo-nozzle size are supported by REX
Once the optimum humidity is determined simply push a button and automatically exchange the humidity-nozzle with the cryo-nozzle. The nozzle exchange is done in a quick and non-linear movement, leading to the flash-cooling of the crystal while preserving the humidity induced crystal properties. The frozen crystal is now ready for the collection of a final data-set.
Alignment & safety
Both nozzles are mounted onto REx and aligned only once. They always remain aligned with respect to the sample position no matter how many automatic nozzle movements you perform. During an experiment external beamline users may exchange nozzles rapidly and at any time without a helping hand from the beamline scientist. Finished the time when loosely or wrongly fixed nozzles let to collision accidents.