- 1 µm sphere of confusion (radius, @ 100 deg/s)
- Horizontal Ω-axis
- Fast Ω-axis rotation speed: 500 deg/s
Efficient integrated tools
- On-axis video microscope (OAV) for parallax-free sample visualization
- Movable beam-stop:
- Beamstop 400-80 (distance to the sample: 28 to 80 mm)
- Beamstop 400-60 (distance to the sample: 8 to 60 mm)
High level of integration
- Software integration adapted to your beamline
- Multi-device servers: TINE, TANGO, EPICS, …
- Compatible with sample changer robot
High precision single crystal diffractometer
1 µm Sphere Of Confusion (SOC)
The MD2-S reaches a 1 µm sphere of confusion (radius, @ 100 deg/s, with a SmartMagnet sample holder mounted on the Ω-axis) with an excellent repeatability and reliability.
This micrometer SOC is achieved by an optimized design combining high precision components with a support structure preventing parasitic vibrations and deformations.
The MD2-S has a high accuracy which is perfectly suited for single crystal X-ray diffractometry and advanced data collection strategies. The MD2-S reaches a static precision of ± 0.5 mdeg and an excellent dynamic precision of ±2 mdeg for its Ω-axis (@ 10 deg/s rotation speed, with a SmartMagnet sample holder mounted on the Ω-axis).
Enhanced sample visualization
Parallax-free sample visualization
The MD2-S integrates ARINAX well-known On-Axis Video microscope (OAV) with an optical axis along the x-ray beam path. The resulting parallax-free image is delivered at high spatial resolution (350 350 nm² per pixel) and excellent contrast. The outstanding in situ sample imaging is possible thanks to the unique objective design, developed by the European Molecular Biology Laboratory (EMBL).
Video assisted centering system
The MD2-S software offers a video assisted sample centering functionality taking full advantage of the OAV performances. This “three click-centering” functionality gives the possibility to:
– Localize the beam
– Align the sample to the beam position
– Center the sample within the beam
Advanced data collection strategies
The MD2-S software is able to coordinate simultaneously multi-axe movements, the prerequisite for advanced x-ray data collection strategies using grid scans, helical scans or serial crystallography. The control software supports all of these scanning techniques on different levels.
Advanced Detector Trigger modes
The MD2-S diffractometer is compatible with numerous trigger modes to synchronize the different motor positions with the x-ray detector.
The MD2-S diffractometer provides continuously the exact sample position & orientation to the detector which then, are filed for each diffraction image taken by the detector.
Kappa goniometer head & In situ crystallography
The MD2-S standard SmartMagnet sample holder can be exchanged with different goniometer heads:
– The Mini-Kappa, MK3, is a multi-axis goniometer head that provides two additional axes of rotation, called « kappa » and « phi », for advanced crystal alignment strategies (Brockhauser, 2013).
– The Plate Manipulator is a motorized 96-well plate holder mounted on the Ω-axis. This goniometer head gives access to high accuracy in situ crystallography.
To offer the best flexibility to users, the SmartMagnet, the Mini-Kappa and the Plate Manipulator are designed to be easily mounted and dismounted: switching between these goniometer heads is done within a couple of minutes and no trained personnel is necessary.
Integrated Movable Beamstop
The MD2-S integrates a movable beamstop which is optimally suited for single crystal diffraction with a minimum/maximum sample-to-beamstop distance of 8 mm/60 mm. The movable beamstop is also useful for in situ crystallography with 96-well plates.
Arinax & beamline integration
For over 12 years Arinax has developed strong competences in beamline integration. Thanks to its expertise Arinax can entirely integrate the MD2-S into beamline specific software like MXCube or Blu-Ice.The MD2-S software supports different multi-device servers: TINE, TANGO and EPICS.
In addition, the MD2-S is fully configurable for automated beamline operation sample changer robots (e.g. 6-axis sample changer robot)
ARINAX supplies interface electronics for the communication with sample changer robots from IRELEC-ALCEN.
(2017) J Synchrotron Radiat.; 24(Pt 1): 323–332. « P13, the EMBL macromolecular crystallography beamline at the low-emittance PETRA III ring for high- and low-energy phasing with variable beam focusing«
(2016) Acta Crystallogr D Struct Biol.; 72(Pt 3): 413–420. »Facilitating best practices in collecting anomalous scattering data for de novo structure solution at the ESRF Structural Biology Beamlines »
|On-axis video microscope||(OAV)|
|Sphere of confusion||1 µm radius, @ 100 deg/s|
|Maximum rotation speed||500 deg/s|
|Angular resolution||0.1 mdeg|
|Angular following error||± 2 mdeg RMS @10 deg/s|
|User interface||JAVA Control application|
|Beamline software integration||Customizable (e.g. MXCube, Blu-Ice)|
|Multi-device servers||TINE, TANGO, EPICS|
|Sample changer robot||Robot hardware & software integration|
|Control features||Parallax-free sample visualization
semi-automatic sample centering
4D Data collection strategies
Advanced detector synchronization modes
Selectable beam shaping tools
|Beamstop 400-80||Distance to the sample: 28 to 80 mm|
|Beamstop 400-60||Distance to the sample: 8 to 60mm|
|Voltage||110 VAC to 240 VAC|
|Frequency||50 to 60 Hz|
|Electric power||1000 W|
|Depth x Width x Height||432 x 620 x 476 mm3|
|Diffractometer only||100 kg|